Hotels in Santo Domingo, DO

Santo Domingo draws visitors for local culture, historic sites, and authentic regional experiences. Hotels near central Santo Domingo offer easy access to attractions, dining, and public transportation.

Find hotels in Santo Domingo, DO near landmarks, attractions, and the best neighborhoods. Whether you need hotels in Santo Domingo for business or leisure, Lodgegrid helps you decide where to stay based on location—then book with trusted partners.

Available Hotels in Santo Domingo, DO

Found 50 hotels in Santo Domingo, DO.

• Novus Plaza Hodelpa

  3 star hotels in Santo Domingo, DO

  Address: El Conde Esquina Hostos

  City: Santo Domingo

  Guest Rating: 9.2/10

  Prices from USD 66.63 per night

  Based on 239 reviews

• Hodelpa Caribe Colonial

  4 star hotels in Santo Domingo, DO

  Address: Isabel La Catolica No. 159

  City: Santo Domingo

  Guest Rating: 8.4/10

  Prices from USD 106.88 per night

  Based on 613 reviews

• Cataleya Hotel

  0

  Address: 52 Calle Mercedes

  City: Santo Domingo

  Guest Rating: 8.3/10

  Prices from USD 68.01 per night

  Based on 1267 reviews

• Hodelpa Nicolás de Ovando

  5 star hotels in Santo Domingo, DO

  Address: Calle Las Damas Cuidad Colonia

  City: Santo Domingo

  Guest Rating: 8.7/10

  Prices from USD 271.3 per night

  Based on 1003 reviews

• RIG Casa Conde

  3 star hotels in Santo Domingo, DO

  Address: Calle Peatonal El Conde 511

  City: Santo Domingo

  Guest Rating: 7.4/10

  Prices from USD 48.73 per night

  Based on 60 reviews

• RIG Casa Conde

  3 star hotels in Santo Domingo, DO

  Address: Calle El Conde 511

  City: Santo Domingo

  Guest Rating: 7.2/10

  Prices from USD 54.35 per night

  Based on 480 reviews

• Kimpton Las Mercedes by IHG

  4 star hotels in Santo Domingo, DO

  City: Santo Domingo

  Guest Rating: 9.4/10

  Prices from USD 291.25 per night

  Based on 84 reviews

• Hostal Boutique 53

  3 star hotels in Santo Domingo, DO

  Address: Avenida Dr Delgado

  City: Santo Domingo

  Guest Rating: 9/10

  Prices from USD 43.81 per night

  Based on 60 reviews

• Hotel Boutique Casa Sánchez

  3 star hotels in Santo Domingo, DO

  Address: Calle Sanchez No. 260

  City: Santo Domingo

  Guest Rating: 8.3/10

  Prices from USD 133.47 per night

  Based on 1814 reviews

• Billini Hotel, Historic Luxury

  5 star hotels in Santo Domingo, DO

  Address: Padre Billini #256 & 258

  City: Santo Domingo

  Guest Rating: 8.7/10

  Prices from USD 250.37 per night

  Based on 280 reviews

• Hotel El Señorial 58

  3 star hotels in Santo Domingo, DO

  Address: Pdte. Vicini Burgos

  City: Santo Domingo

  Guest Rating: 7.6/10

  Prices from USD 49.81 per night

  Based on 52 reviews

• La Casona Dorada

  3 star hotels in Santo Domingo, DO

  Address: AV. INDEPENDENCIA 255

  City: Santo Domingo

  Guest Rating: 7.4/10

  Prices from USD 58.86 per night

  Based on 132 reviews

• Napolitano Hotel

  3 star hotels in Santo Domingo, DO

  Address: Av. George Washington No. 51

  City: Santo Domingo

  Guest Rating: 7.9/10

  Prices from USD 104 per night

  Based on 819 reviews

• RIG Puerto Malecón

  0

  Address: Calle Pina, No. 56

  City: Santo Domingo

  Guest Rating: 7.9/10

  Prices from USD 73.23 per night

  Based on 1066 reviews

• Crowne Plaza Santo Domingo by IHG

  4 star hotels in Santo Domingo, DO

  Address: Ave. George Washington 218

  City: Santo Domingo

  Guest Rating: 8.9/10

  Prices from USD 152.03 per night

  Based on 301 reviews

• Barceló Santo Domingo

  5 star hotels in Santo Domingo, DO

  Address: Maximo Gomez-Esq 27 de Febrero

  City: Santo Domingo

  Guest Rating: 8.6/10

  Prices from USD 121.33 per night

  Based on 1010 reviews

• Casas del XVI

  5 star hotels in Santo Domingo, DO

  Address: Calle Padre Billini No. 252

  City: Santo Domingo

  Guest Rating: 8.8/10

  Prices from USD 393.79 per night

  Based on 214 reviews

• Sheraton Santo Domingo

  5 star hotels in Santo Domingo, DO

  Address: 365 George Washington Avenue

  City: Santo Domingo

  Guest Rating: 9.6/10

  Prices from USD 268.36 per night

  Based on 395 reviews

• Renaissance Santo Domingo Jaragua Hotel & Casino

  4 star hotels in Santo Domingo, DO

  Address: Avenida George Washington 367

  City: Santo Domingo

  Guest Rating: 9.4/10

  Prices from USD 209.41 per night

  Based on 535 reviews

• Hotel San Marco

  3 star hotels in Santo Domingo, DO

  Address: Santiago 752

  City: Santo Domingo

  Guest Rating: 8.7/10

  Prices from USD 128.4 per night

  Based on 107 reviews

• Royal Palace Hotel

  3 star hotels in Santo Domingo, DO

  Address: Av Abraham Lincoln 116

  City: Santo Domingo

  Guest Rating: 7.1/10

  Prices from USD 44.23 per night

  Based on 123 reviews

• Empyrean Art Deco

  3 star hotels in Santo Domingo, DO

  Address: Calle Isabel La Católica 314

  City: Santo Domingo

  Guest Rating: 8.7/10

  Based on 77 reviews

• Empyrean Art Deco

  3 star hotels in Santo Domingo, DO

  City: Santo Domingo

  Guest Rating: 8.7/10

  Based on 75 reviews

• Island Life Hostel

  3 star hotels in Santo Domingo, DO

  Address: Calle Isabel La Catolica #356

  City: Santo Domingo

  Guest Rating: 8.1/10

  Based on 1242 reviews

• Gran Hotel Europa Santo Domingo, Trademark by Wyndham

  3 star hotels in Santo Domingo, DO

  Address: Arzobispo Merino No. 109, Zona Colonial,

  City: Santo Domingo

  Guest Rating: 8.6/10

  Based on 171 reviews

• Jardin Colonial Boutique Hotel

  3 star hotels in Santo Domingo, DO

  Address: Calle La Mercedes # 59

  City: Santo Domingo

  Guest Rating: 8.8/10

  Based on 32 reviews

• Hotel Conde de Penalba

  3 star hotels in Santo Domingo, DO

  Address: Calle El Conde 111 esq Arzobispo Meriño

  City: Santo Domingo

  Guest Rating: 8.6/10

  Based on 859 reviews

• Mosquito Boutique Hotel Zona Colonial

  3 star hotels in Santo Domingo, DO

  Address: Calle Merino N. 266

  City: Santo Domingo

  Guest Rating: 8.4/10

  Based on 595 reviews

• Hotel Cana Palma Zona Colonial

  0

  Address: Calle Arzobispo Merino #552, Zona Colonial

  City: Santo Domingo

  Guest Rating: 8.4/10

  Based on 589 reviews

• Colonial 154 H Boutique

  4 star hotels in Santo Domingo, DO

  Address: Calle General Luperon #154

  City: Santo Domingo

  Guest Rating: 8.5/10

  Based on 116 reviews

• Boutique Hotel Palacio

  4 star hotels in Santo Domingo, DO

  Address: Calle Duarte 106

  City: Santo Domingo

  Guest Rating: 8.2/10

  Based on 410 reviews

• Estancia Riviera Colonial I

  0

  Address: Calle María Trinidad Sánchez 1, N3-A7, Villa Duarte.

  City: Santo Domingo

  Guest Rating: 8.7/10

  Based on 6 reviews

• VBermor Hotel

  2 star hotels in Santo Domingo, DO

  Address: 54 C. Mercedes

  City: Santo Domingo

  Guest Rating: 6.4/10

  Based on 5 reviews

• FIXIE LOFTS - Colonial Villa Suites with Pool

  0

  Address: 314 C. Arzobispo Meriño

  City: Santo Domingo

  Guest Rating: 9/10

  Based on 74 reviews

• FIXIE LOFTS - Colonial Villa Suites with Pool

  0

  Address: Calle Arzobispo Meriño 314

  City: Santo Domingo

  Guest Rating: 9/10

  Based on 73 reviews

• Hotel La Colonia

  2 star hotels in Santo Domingo, DO

  Address: 110 Calle Isabel La Católica

  City: Santo Domingo

  Guest Rating: 8.2/10

  Based on 117 reviews

• Sol Colonial

  2 star hotels in Santo Domingo, DO

  City: Santo Domingo

  Guest Rating: 9.5/10

  Based on 5 reviews

• Habitación Independiente Zona Colonial

  0

  Address: 109 Calle General Cabral Segundo nivel

  City: Santo Domingo

  Guest Rating: 8.4/10

  Based on 14 reviews

• Hotel Casa Aluge

  3 star hotels in Santo Domingo, DO

  Address: Calle Salome Urena entre calle

  City: Santo Domingo

  Guest Rating: 8/10

  Based on 76 reviews

• Hotel Tau Art Residence

  3 star hotels in Santo Domingo, DO

  Address: Calle Jose Reyes 206, Ciudad Colonial

  City: Santo Domingo

  Guest Rating: 7.8/10

  Based on 54 reviews

• VBermor Hotel

  0

  Address: Calle mercedes numero 54 zona colonial

  City: Santo Domingo

  Guest Rating: 7.7/10

  Based on 182 reviews

• Hotel D' Cornelio & Spa

  2 star hotels in Santo Domingo, DO

  Address: 159 C. Mercedes

  City: Santo Domingo

  Guest Rating: 5.6/10

  Based on 16 reviews

• Kimpton Las Mercedes by IHG

  0

  Address: Calle Las Mercedes #155

  City: Santo Domingo

  Guest Rating: 9.2/10

  Based on 157 reviews

• El Beaterio Casa Museo

  3 star hotels in Santo Domingo, DO

  Address: Calle Duarte número 8, Zona Colonial

  City: Santo Domingo

  Guest Rating: 8.7/10

  Based on 1091 reviews

• Aparta Hotel Roma

  3 star hotels in Santo Domingo, DO

  Address: Calle 19 de Marzo 103, Zona Colonial

  City: Santo Domingo

  Guest Rating: 8.1/10

  Based on 78 reviews

• Hostel Gato Colonial

  0

  Address: Calle Juan Isidro Perez

  City: Santo Domingo

  Guest Rating: 8/10

  Based on 15 reviews

• Hotel Guarocuya

  2 star hotels in Santo Domingo, DO

  Address: 162 C. Mercedes

  City: Santo Domingo

  Guest Rating: 7/10

  Based on 58 reviews

• Hotel Villa Colonial

  3 star hotels in Santo Domingo, DO

  Address: Calle Sánchez 157

  City: Santo Domingo

  Guest Rating: 9.6/10

  Based on 267 reviews

• Luca Hotel by Heritage Residences Signature Collection

  3 star hotels in Santo Domingo, DO

  Address: Calle 19 de Marzo No. 164

  City: Santo Domingo

  Guest Rating: 9/10

  Based on 141 reviews

• Casa Adefra Boutique Hotel Zona Colonial

  3 star hotels in Santo Domingo, DO

  Address: 462 C. El Conde

  City: Santo Domingo

  Guest Rating: 9.6/10

  Based on 48 reviews

Why Use Lodgegrid for Santo Domingo, DO

• Find hotels near landmarks and popular attractions in Santo Domingo, DO
• See the best areas and neighborhoods to stay
• Compare hotels by location, not just price
• Decide where to stay—then book with trusted partners